Not known Facts About akorn codeine
Not known Facts About akorn codeine
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Existence-Threatening Respiratory Depression Tell sufferers of the chance of everyday living-threatening respiratory melancholy, which includes details that the danger is biggest when setting up promethazine HCl and codeine phosphate oral Answer and that it could possibly occur even at advisable dosages [see Warnings and Safety measures (five.
Promethazine is metabolized via the liver to a number of inactive metabolites for instance sulfoxides of promethazine, N-demethylpromethazine along with other glucuronides.
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Put the mixture in a very container for instance a sealed plastic bag and toss it absent while in the household trash. You may also observe your point out or neighborhood tips regarding how to safely throw away Promethazine Hydrochloride and Codeine Phosphate Oral Alternative.
Overdose of codeine in Grown ups has long been related to fatal respiratory melancholy, and using codeine in children more youthful than twelve decades of age has been associated with lethal respiratory melancholy when utilized as recommended [see Warnings and Safety measures (five.
In case your pharmacist is unable to obtain an analogous generic medication on the 1 you're working with from A different manufacturer, Tsourounis suggests getting in touch with your healthcare provider to discuss if you will find another choices available.
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Good evaluation from the individual, right prescribing practices, periodic re-evaluation of therapy, and appropriate dispensing and storage are acceptable measures that aid to Restrict abuse of opioid medications.
Unresponsive Cough The dosage of promethazine HCl and codeine phosphate oral Alternative should not be enhanced if cough fails to respond; an unresponsive cough really should be reevaluated in five days or sooner for probable underlying pathology, including overseas system or lessen respiratory tract disease [see Dosage and Administration (two.three)].
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Opioids are sought by drug abusers and those with habit Ailments and therefore are subject matter to legal diversion. Contemplate these hazards when prescribing or dispensing promethazine HCl and codeine phosphate oral Resolution. Approaches to scale back these hazards consist of prescribing the drug in the smallest suitable amount and advising the individual on the proper disposal of unused drug [see Patient Counseling Facts (17)].
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Impaired secretion from sweat glands subsequent poisonous doses more info of prescription drugs with anticholinergic Unwanted side effects might predispose to hyperthermia.